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Semen and hormonal parameters in men with chronic hepatitis C infection |
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| Authors: | Hofny Eman Riaad M Ali Mohammed Essam M Taha Emad A Nafeh Hanan M Sayed Doaa Samir Abdel-Azeem Hanan G Abdou Ehab Fawzy Kamal Ghada Mostafa Mostafa Taymour |
| Affiliation: | a Dermatology and Andrology Department, Faculty of Medicine, Assiut University, Assiut, Egypt b Tropical Medicine, Gastroenterology and Hepatology Department, Faculty of Medicine, Assiut University, Assiut, Egypt c Clinical Pathology Department, Faculty of Medicine, Assiut University, Assiut, Egypt d Tropical Medicine, Gastroenterology and Hepatology Department, Sohag University, Sohag, Egypt e Andrology and Sexology Department, Faculty of Medicine, Cairo University, Cairo, Egypt |
| Abstract: | Male patients with chronic hepatitis C virus (HCV) infection (n = 57) demonstrated a statistically significant decrease in semen volume, sperm count, and progressive sperm motility and a statistically significant increase in abnormal sperm morphology compared with healthy controls (n = 40). The duration of the HCV infection was negatively correlated with semen volume and sperm motility where the HCV RNA viral load was negatively correlated with sperm count and sperm motility. Chronic HCV patients had statistically significantly lower total serum testosterone and higher serum E(2) and prolactin levels compared with healthy controls. |
| Keywords: | Hepatitis HCV semen hormones viral load |
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