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Effect of vaginal probiotic lactobacilli on in vitro-induced sperm lipid peroxidation and its impact on sperm motility and viability |
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| Authors: | Barbonetti Arcangelo Cinque Benedetta Vassallo Maria Rosaria Caterina Mineo Salvatore Francavilla Sandro Cifone Maria Grazia Francavilla Felice |
| Affiliation: | a Andrology Unit, Department of Internal Medicine, University of L’Aquila, L’Aquila, Italy b Center for Clinical Research, San Raffaele Sulmona, Sulmona, Italy c Department of Experimental Medicine, University of L’Aquila, L’Aquila, Italy |
| Abstract: | A combination of three selected strains of lactobacilli (Lactobacillus brevis [CD2], L. salivarius [FV2], and L. plantarum [FV9]), whose effectiveness in treating bacterial vaginosis in the form of vaginal tablets has been reported recently, prevented sperm lipid peroxidation that was induced in vitro by a ferrous ion promoter, thus preserving sperm motility and viability. This finding suggests the potential of vaginal probiotic lactobacilli for protecting human spermatozoa from radical oxygen species in the presence of vaginal disorders, thereby improving the fertilization potential of the female host. |
| Keywords: | Probiotic lactobacilli bacterial vaginosis human spermatozoa lipid peroxidation sperm motility |
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