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Modulation of syndecans in the uterus throughout the menstrual cycle: comparison between endometrium and myometrium
Authors:Lorenzi Teresa  Turi Angelo  Morroni Manrico  Vitali Alessandra  Tranquilli Andrea L  David Guido  Castellucci Mario  Marzioni Daniela
Affiliation:a Department of Molecular Pathology and Innovative Therapies, Università Politecnica delle Marche, Ancona, Italy
b Department of Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy
c Department for Molecular and Developmental Genetics, VIB, Leuven, Belgium
d Centre for Human Genetics, University of Leuven, Leuven, Belgium
Abstract:Immunohistochemistry and semiquantitative analysis were used to examine and compare the expression of syndecans 1-4 in the endometrium and myometrium throughout the menstrual cycle. Syndecans molecules show different temporal and spatial expression during the menstrual cycle, and the modulation of syn-2 expression is statistically significantly correlated to morphologic and functional changes of the endometrium, particularly in the periovulatory period.
Keywords:Endometrium   immunohistochemistry   menstrual cycle   myometrium   syndecans   uterus
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