视网膜脱离手术前后的多焦视网膜电图比较

目的探讨视网膜脱离手术前后多焦视网膜电图(multifocal electroretinography, mERG)的改变及其临床应用价值。　方法应用VERIS Science ^TM4.0对18例(18只眼)裂孔源性视网膜脱离患者手术前后分别进行mERG检查，并对不同区域的mERG进行了比较。结果手术前脱离区a、b波的潜伏期比非脱离区明显延长，差异有显著性的意义(t＝4.541、t＝6.784，P<0.01)，脱离区a、b波的振幅密度明显小于非脱离区，差异有显著性的意义(t=3.680、t＝4.257，P<0.01)；手术后中心凹、黄斑区、黄斑外区及全测试区的a、b 波的振幅密度均比手术前明显提高(P<0.01)，但是a、b波的潜伏期手术前后则无明显变化(P>0.05)；手术后原脱离区a、b波的振幅密度均比术前有明显提高(P<0.05)。　结论视网膜脱离复位术后视网膜功能有一定提高，mERG是评价术后视网膜功能恢复的有用工具，振幅密度比潜伏期更敏感。(中华眼底病杂志,2001,17:264-267)

The comparison of multifocal electroretinogram before and after retinal detachment surgery

Objective To explore the changes of multifocal electroretinogram (mERG) before and after retinal detachment surgery and its clinical significance. Methods Eighteen patients suffered from rhegmatogenous retinal detachment underwent mERG before and after surgery using VERIS Science TM 4.0. The mERG at different area was compared between preoperative and postoperative surgery. Results Preoperatively, the latencies of a wave and b wave in detached area were statistically longer than in attached area ( t =4.541 and 6.784, P< 0.01). The amplitude densities of a wave and b wave were statistically smaller in detached area than in attached area ( t =3.680 and 4.257, P< 0.01). Postoperatively, the amplitude densities of a wave and b wave at fovea, macula, perimacular area and whole tested area significantly improved. Statistical difference was found before and after surgery, but no statistical difference was found in the latencies of a wave and b wave. The amplitude densities of a wave and b wave in the preoperative detached area were statistically larger after surgery than before surgery ( P< 0.05). Conclusions After retinal detachment surgery, the responses of mERG improve to some degree. mERG was a promising tool to evaluate the recovery of retinal function after surgery. The amplitude densities are more sensitive than the latencies to evaluation of retinal function.