Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
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| Authors: | Jun Hyeok Kim Bo Da Nam Jung Hwa Hwang Dong Won Kim Ki-Up Kim Young Woo Park |
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| Affiliation: | aDepartment of Radiology, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea;bDepartment of Pathology, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea;cDepartment of Allergy and Respiratory Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea;dDepartment of Cardiothoracic Surgery, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea. |
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| Abstract: | Rationale:Necrotizing sarcoid granulomatosis (NSG) has recently been termed “sarcoidosis with NSG pattern” for the disease entity representing nodular sarcoidosis with granulomatous pulmonary angiitis. It is characterized by sarcoid-like granulomas, vasculitis, and a variable degree of necrosis. Its rarity and nonspecific clinical symptoms can easily lead to misdiagnosis or delayed diagnosis.Patient concerns:We report a 67-year-old female with a biopsy-confirmed sarcoidosis with NSG pattern mimicking pulmonary malignancy on initial chest computed tomography scan.Diagnoses:Sarcoidosis with NSG pattern.Interventions:The patient underwent video-assisted thoracoscopic surgery with a lung biopsy. No further treatment was performed after the lung biopsy.Outcomes:Follow-up imaging studies revealed spontaneous regression of the disease after 2 months.Lessons:Awareness of this rare benign disease entity and overlapping radiologic manifestations with pulmonary malignancy or other granulomatous diseases can be helpful for making a precise diagnosis with a better differential diagnosis. |
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| Keywords: | multiple pulmonary nodule pulmonary neoplasm sarcoidosis vasculitis |
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