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Synthesis of imidazo[2,1-b]thiazoles as herbicides
Institution:1. Department of Chemistry, Krishna University, Machilipatnam, Andhra Pradesh 521 001, India;2. Department of Chemistry, University College of Engineering (Autonomous), Jawaharlal Nehru Technological University, Kakinada, Andhra Pradesh 533003, India;3. Pharmaceutical Chemistry Department, School of Pharmacy, International Medical University, 126, Jalan Jalil Perkasa 19 Bukit Jalil, Kuala Lumpur 57000, Malaysia;4. Vishnu Institute of Pharmaceutical Education & Research (VIPER), Narsapur, Medak, Telangana 502313, India;5. Department of Pharmaceutical Chemistry, Maharishi Arvind College of Pharmacy, Ambabari Circle, Jaipur, Rajasthan 302 039, India
Abstract:A series of imidazo2,1-b]thiazoles bearing halogens or a sulfonylurea group or an imidazolidone group, were synthesized and subjected to pre- and post-emergence herbicidal tests. 5-Bromo-6-(3-pyridyl)-2,3-dihydroimidazo2,1-b]thiazole (4e) and 6-(2,3,4-trichlorophenyl)-2,3-dihydroimidazo2,1-b]thiazole-5-carboxylic acid (8b) showed moderate activity in the post-emergence herbicidal tests only.
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