| galectin-3与几种甲状腺疾病的关系 |
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| 引用本文： | 杨婷婷,程若川.galectin-3与几种甲状腺疾病的关系[J].中国普外基础与临床杂志,2011,18(8). |
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| 作者姓名： | 杨婷婷 程若川 |
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| 作者单位： | 昆明医学院第一附属医院胃肠甲状腺外科,云南昆明,650031 |
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| 摘 要： | 目的 研究galectin-3的结构、配体、组织分布与肿瘤的关系及其在几种甲状腺疾病中的表达情况.方法 对相关文献进行综述分析.结果 galectin-3在正常细胞及肿瘤细胞中表达,调节细胞的生长、分化、黏附、凋亡和血管形成,参与肿瘤细胞的侵袭和转移.结论 galectin-3可作为鉴别甲状腺良恶性肿瘤的参考指标.
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| 关 键 词： | galectin-3 甲状腺乳头状癌 甲状腺腺瘤 桥本甲状腺炎 亚急性甲状腺炎 |
Relationship Between Galectin-3 and Thyroid Diseases |
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| YANG Ting-ting,CHENG Ruo-chuan.Relationship Between Galectin-3 and Thyroid Diseases[J].Chinese Journal of Bases and Clinics In General Surgery,2011,18(8). |
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| Authors: | YANG Ting-ting CHENG Ruo-chuan |
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| Institution: | YANG Ting-ting,CHENG Ruo-chuan.Department of Gastrointestinal and Thyroid Surgery,The First Affiliated Hospital of Kunming Medical College,Kunming 650031,Yunnan Province,China.com.cn |
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| Abstract: | Objective To investigate the structure,ligand,and tissue distribution of galectin-3,the relationship of galectin-3 with tumor and the expression of galectin-3 in several thyroid diseases.Methods Related articles were reviewed.Results Galectin-3 was expressed in normal and tumor cell that regulated cell growth,differentiation,adhesion,apoptosis,and angiogenesis,which participated invasion and metastasis of tumor.Conclusion Galectin-3 may be used to discriminate benign and malignant thyroid tumor. |
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| Keywords: | Galectin-3 Papillary thyroid carcinoma Thyroid adenoma Hashimoto's thyroiditis Subacute thyroid inflammation |
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