胎儿型纤维连接蛋白与早产

目的：探讨胎儿型纤维连接蛋白与早产的关系，为早产诊断寻找新的方法。方法：应用美国ＡＤＥＺＡ公司的胎儿型纤维连接蛋白（ｆＦＮ）试剂盒，以酶联免疫吸附（ＥＬＩＳＡ）法，对３８例先兆早产孕妇（研究组）和４３例正常孕妇（对照组）的宫颈粘液中ｆＦＮ进行检测，以ｆＦＮ≥２５０μｇ／Ｌ为阳性。结果：研究组孕妇宫颈粘液中，ｆＦＮ阳性率明显高于对照组。结论：ｆＦＮ对早产的诊断有重要的参考价值，为早产的诊断及预后判断提供了一种新的监测手段。

Fetal Fibronectin and Preterm Birth

Objective: To determine whether fetal fibronectin is a sensitive test for the diagnosis and prediction of preterm birth. Methods: Fetal fibronectin was measured by enzyme labeled immunosorbent assay (ELISA) methods in sample of cervical secretion from 38 women with threatened preterm delivery (study group) and 43 normal pregnanty women with same gestational weeks (control group). Results: The postive rate of fetal fibronectin in women with threatened preterm birth was significantly higher than that in the normal control group. Conclusions: Fetal fibronectin is an important marker. It can be used for diagnosis and prediction of preterm birth.