阻塞性睡眠呼吸暂停低通气综合征患者睡眠结构分析

目的分析不同严重程度阻塞性睡眠呼吸暂停低通气综合征（OSAnS）患者的睡眠结构特点。方法选择确诊为OSAHS的成年患者168例为观察组，并选取同期与其条件相当的单纯鼾症者136例作为对照组。采用多导睡眠监测仪（PSG）对所有入选者进行整夜监测，对比分析不同严重程度OSAHS患者以及单纯鼾症者夜间睡眠结构情况。结果OSAHS患者组与单纯鼾症组相比，睡眠时间与睡眠效率差异无统计学意义（P〉0．05），而睡眠I期所占比例升高，睡眠Ⅱ期、SWS相和REM相所占比例显著降低（均P〈0．05）。睡眠结构紊乱在重度分级中（AHI≥40）差异更显著。结论OSAHS患者的浅睡眠比单纯鼾症者明显增加，而深睡眠和快动眼睡眠比单纯鼾症者明显减少；随着OSAHS病情分级的加重，对睡眠结构紊乱的影响也更加明显。

Clinical analysis of the sleep structure in patients with obstructive sleep apnea syndrome

Objective To analyze the features of sleep structure of patients with different severity of obstructive sleep apnea syndrome (OSAHS). Methods 168 adult patients with OSAHS were selected as study group, and 136 patients with simple snoring were selected as control group. All patients were monitored with polysonmography (PSG) throughout the night ,and compared the sleep structure of patients with different severity of OSAHS and simple snoring at night. Results OSAHS group compared with simple snoring group,sleep time and sleep efficiency were not significantly different(P ＞ 0. 05);while OSAHS group had increased stage I,and decreased stage Ⅱ, SWS％ and REM％, the differences were statistically significance (P ＜ 0.05 ). The difference in severe classification group( AHI ≥40) was more significant. Conclusion OSAHS patients presented more drowsy sleep, and less deep sleep, and with the grade of OSAHS increasing,the influence of sleep structure was more obvious.