强脉冲光联合脉冲染料激光治疗鲜红斑痣的临床疗效观察

目的探讨强脉冲光(IPL)联合脉冲染料激光(PDL)治疗紫红型和增厚型鲜红斑痣(PWS)的疗效。方法紫红型和增厚型PWS患者120例,随机分为治疗组60例,对照组60例。治疗组先用IPL治疗3次,每次间隔2～4周,再用PDL治疗5～8次,PDL治疗每次间隔2～3个月;对照组仅行PDL治疗,治疗方法及间隔时间同治疗组。治疗3～8次后比较两组患者的疗效和不良反应。结果治疗8次后总有效率和治愈率治疗组分别为55.0%和16.7%;对照组分别为33.3%、10.0%。两组患者治疗次数与疗效呈正相关(P<0.05)。治疗组2例(3.3%)出现增生性瘢痕,2例(3.3%)出现色素减退,1例(1.7%)出现色素沉着。对照组1例(1.7%)出现增生性瘢痕,4例(6.7%)出现色素沉着,4例(6.7%)出现色素减退。随访3个月内,两组色素沉着伴均有不同程度的消退及减淡,色素减退和增生性瘢痕3个月内改善不明显。结论 IPL联合PDL治疗紫红型和增厚型PWS疗效可靠,不良反应较少。

Combined Treatment of Intense Pulsed Light With Pulsed Dye Laser for Port Wine Stains: a Clinical Observation

Objective To explore and evaluate the intense pulsed light(IPL) with pulsed dye laser(PDL) treatment for amaranthine and thickening types of port wine stains(PWS) and its efficacy. Methods Totally 120 cases of patients with amaranthine and thickening types of PWS,were randomly and equally divided into treatment group and control group.The treatment group,first received three times of IPL,with each 2-4 weeks interval,then 5-8 times of PDL with each 2-3 months interval vs only PDL with same times and interval...