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左氧氟沙星治疗医院获得性肺炎疗效观察
引用本文:欧阳国栋,蔡冰,吴渊,廖雁. 左氧氟沙星治疗医院获得性肺炎疗效观察[J]. 中国基层医药, 2011, 18(19): 2643-2644. DOI: 10.3760/cma.j.issn.1008-6706.2011.19.026
作者姓名:欧阳国栋  蔡冰  吴渊  廖雁
作者单位:1. 佛山市顺德区慢性病防治中心结防科,广东省佛山,528300
2. 佛山市顺德区慢性病防治中心皮肤科,广东省佛山,528300
3. 佛山市顺德区慢性病防治中心医务办,广东省佛山,528300
摘    要:目的探讨左氧氟沙星治疗医院获得性肺炎的临床效果。方法134例医院获得性肺炎患者在知情同意下按入院顺序随机分为观察组和对照组各67例,对照组给予阿奇霉素治疗,观察组给予左氧氟沙星治疗,观察比较两组显效率和总有效率。结果经过治疗,观察组显效51例、有效13例、无效3例、显效率75.0%、总有效率93.3%,对照组分别为38例、17例、12例、51.7%、81.7%,观察组显效率和总有效率均明显高于对照组(X2=4.818、4.804,均P〈0.05)。两组均未发生严重不良反应。结论左氧氟沙星治疗医院获得性肺炎可获得较好的临床治疗效果,不良反应轻。

关 键 词:交叉感染  肺炎  左氧氟沙星  阿奇霉素

The clinical effect of levofloxacin used on patients with hospital acquired pneumonia (HAP)
OUYANG Guo-dong,CAI Bing,WU Yuan,HAO Yan. The clinical effect of levofloxacin used on patients with hospital acquired pneumonia (HAP)[J]. Chinese Journal of Primary Medicine and Pharmacy, 2011, 18(19): 2643-2644. DOI: 10.3760/cma.j.issn.1008-6706.2011.19.026
Authors:OUYANG Guo-dong  CAI Bing  WU Yuan  HAO Yan
Affiliation:OUYANG Guo-dong , CM Bing, WU Yuan,LIA O Yan. Department of Tuberculosis Prevention, Centers for Disease Control of Chronic Disease of Shunde District, Foshan , Guangdong 538300, China
Abstract:Objective To explore the clinical effect of levofloxacin used on patients with HAP. Methods 134 cases of patients with HAP as studied object were randomly divided into observation group and control group,observation group were given therapy of levofloxacin,and control group were given therapy of azithromycin. Results The efficiency cases,effective cases,vain cases in observation group were 51,13 and 3,the efficiency rate and total effective rate were 75.0% and 93.3%, the data in control group were 38,17,12,51.7 % and 81.7 %. The efficiency rate ( x2 =4. 818, P < 0.05 )and total effective rate( x2 =4. 804 ,P < 0.05 ) of observation group was significantly better than that of control group. Conclusion Levofloxacin used on patients with HAP, could acquire good clinical effect,and the side-reactions were light.
Keywords:Cross infection  Pneumonia  Levofloxacin  Azithromycin
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