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Association study of the HLA-A2 allele in Italian Alzheimer disease patients
Authors:Guerini Franca Rosa  Calabrese Elena  Agliardi Cristina  Zanzottera Milena  Franceschi Massimo  Grimaldi Luigi Maria Edoardo  Nemni Raffaello  Ferrante Pasquale
Affiliation:Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation IRCCS, Milan, Italy. fguerini@dongnocchi.it
Abstract:Association of the A2 allele of the human leukocyte antigen (HLA) with Alzheimer disease (AD) is still controversial. The authors evaluated HLA-A2 association with AD in 173 Italian AD patients, considering also the possible interaction with APOE pattern, age of onset and gender. No evidence of any association was found.
Keywords:Alzheimer disease   Human leukocyte antigen   APOE
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