| 6-连氮和6α-甲氧基-6β-取代腙青霉素的合成及抗菌活性 |
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| 引用本文： | 钟伊利,李润荪,雷兴翰.6-连氮和6α-甲氧基-6β-取代腙青霉素的合成及抗菌活性[J].药学学报,1988,23(11):820-824. |
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| 作者姓名： | 钟伊利 李润荪 雷兴翰 |
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| 作者单位： | 上海医药工业研究院 |
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| 摘 要： | 本文报道新颖的6-连氮和6α-甲氧基-6β-取代腙青霉素的合成及引入6α-甲氧基的新方法。这类化合物对一些阴性菌和阳性菌有中等活力,且引入6α-甲氧基之后对细菌的抑制作用增强。
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| 关 键 词： | 6 α-甲氧基-6β-取代腙青霉素 6-连氮青霉素 抑菌活性 |
| 收稿时间： | 1987-10-22 |
Synthesis and antibacterial activity of 6-azino- and 6 alpha-methoxy-6 beta-hydrazono-penicillins |
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| YL Zhong,RS Li and XH Lei.Synthesis and antibacterial activity of 6-azino- and 6 alpha-methoxy-6 beta-hydrazono-penicillins[J].Acta Pharmaceutica Sinica,1988,23(11):820-824. |
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| Authors: | YL Zhong RS Li and XH Lei |
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| Abstract: | 6-Azino-and 6α-methoxy-6β-hydrazono-penicillins were synthesized for the first time and a new general method for the introduction of the methoxy group into the 6α-position of penicillin was disclosed. Some of them show moderate antibacterial activity. |
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| Keywords: | Antibacterial activities 6-Azino-penicillins 6α-Methoxy-6β-hydrazono-penicillins |
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