Hemorrhagic bullous amyloidosis. A histologic, immunocytochemical, and ultrastructural study of two patients |
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| Authors: | T Bieber T Ruzicka R P Linke R von Kries G Goerz O Braun-Falco |
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| Institution: | Department of Dermatology, Ludwig-Maximilians University, Munich, West Germany. |
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| Abstract: | In patients with bullous hemorrhagic amyloidosis of the skin, the skin lesions were the first manifestations of a plasma cell dyscrasia. Both cases were characterized by similar clinical, histologic, and ultrastructural findings showing an intradermal blister within deposits of amyloid substances. Immunohistologic investigations with a panel of antibodies directed against amyloid fibril proteins showed reactivity of the amyloid deposits with an anti-A lambda serum in both patients. |
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