Hemoglobinopathies in the District of Antalya, Turkey |
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| Authors: | Iffet Bircan Sevim i li Asaf Gü ven anda ali Olcay Ye
in Halil Ertu
Ayfer Gü r Gü ven Nejat Akar |
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| Affiliation: | a Department of Pediatrics, Department of Public Health, Department of Pediatric Hematology, Akdeniz University, Antalya, Turkey |
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| Abstract: | A screening program was conducted to ascertain the incidence of hemoglobinopathies in the district of Antalya, Turkey. The survey sample was selected from the household registration forms of health centers by systematic random sampling. Heparinized blood samples were collected from 1,616 subjects from 884 families.
The prevalence of p thalassemia traits with increased Hb A2 was 10.2%. This is higher than that found in previous studies performed in Antalya. The prevalence of abnormal hemoglobins (Hbs) was found to be 0.8%. Four subjects had Hb AS; five had Hb D-Los Angeles (B 121 [GH4] Glu-Gln); one had Hb Ube-2 (68 [E1] Asn-Asp), one had Hb P-Nilotic (fusion between B 22 and) and two had Hb D-like variants. |
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| Keywords: | hemoglobin thalassemia |
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