High-dose epirubicin in chemotherapy refractory non-seminomatous germ cell cancer: a phase II study. EORTC Genito-Urinary Tract Cancer Co-operative Group. EORTC Early Clinical Trials Group. |
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| Authors: | G Stoter A Akdas S D Foss? S B Kaye C J van Groeningen J Renard M van Glabbeke |
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| Affiliation: | Department of Medical Oncology, Rotterdam Cancer Institute, The Netherlands. |
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| Abstract: | Eighteen patients with progressive disseminated, platinum-resistant germ cell tumors were treated with epirubicin 135 mg/m2, every 3 weeks. One patient had stable disease, 17 developed progression. Myelosuppression was dose-limiting. One patient died of neutropenic septicemia. High-dose epirubicin is not active against platinum-resistant germ cell cancer. |
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