胰腺实性假乳头状瘤的诊断和治疗

目的总结胰腺实性假乳头状瘤的诊断和治疗经验。方法回顾性分析我院自2000年6月至2008年2月收治的18例胰腺实性假乳头状瘤患者的临床资料。结果肿瘤位于胰头部4例,胰颈部2例,胰体尾部12例。无特异性临床表现。B超发现胰腺低回声实性或囊实性占位。CT检查发现胰腺低密度占位病变,增强扫描肿瘤周边出现明显不规则强化。血清肿瘤标记物均为阴性。3例行保留脾的胰体尾切除术,6例行胰腺肿瘤摘除术,9例行胰体尾及脾切除术。对18例患者进行随访,平均随访时间11.2个月,均未发现肿瘤复发转移。结论对年轻女性出现的胰腺巨大肿瘤应高度怀疑胰腺实性假乳头状瘤。积极的手术治疗能获得良好的预后。

Clinical Study of Diagnosis and Treatment in Solid-pseudopapillary Tumor of Pancreas

Objective To summarize the experience of diagnosis and treatment in solid-pseudopapillary tumor of pancreas(SPT).Methods A retrospective clinical analysis was made on 18 cases of solid-pseudopapillary tumors of the pancreas admitted from June 2000 to February 2008.Results The tumors of 4 cases were located in the pancreatic head,the tumors of 2 cases was in the neck of pancreas and 12 tu-mors were in the body and tail of pancreas,without specific clinical manifestations.Solid and solid-cysticmasses of low echo were found in pancreas transonic examinations.masses of low density in pancreas was found on CT scan,while irregular enhancement appeared in the cir-cumference of all tumors in enhanced CT scan sequences.Tumor markers in patients'serum were all negative.3 Patients underwent distal pancreatectomy.Simple resection of tumor was performed in 6 cases.9 patients underwent distal pancreatectomy and spleen resection.18 pa-tients were followed up for the average time of 11.2 months.No evidence of relapses and metastasis in these cases was found.Conclusion Huge pancreatic masses of pancreas in young females should suggest the diagnosis of solid-pseudopapillary tumors.Aggressive surgical thera-py can achieve good prognosis in these patients.