六分钟步行试验在慢性支气管炎需做肺功能筛选中的价值

目的 探讨在慢性支气管炎发展为慢性阻塞性肺疾病(COPD)的诊断过程中,6min步行试验(6-MWT)与肺功能的相关性.方法 选择以慢性支气管炎就诊的患者360例,全部做肺功能检测,根据肺功能检测结果 ,符合2002年中华医学会COPD诊断标准,分为COPD组和肺功能正常组.同时做6-MWT,测定6 min步行距离(6-MWD),根据2次6-MWD取其平均值;研究肺功能与6-MWT的相关性,选择50例健康志愿者作对照(对照组).结果 COPD组中142例(95.95%,142/148)6-MWD<420 m.而肺功能正常组中206例(97.17%,206/212)6-MWD≥420 m.6-MWD≥420 m者第1秒用力呼气容积占用力肺活量百分比、第1秒用力呼气容积占预计值百分比、最大通气量均显著高于6-MWD<420m者,差异有统计学意义(JP<0.05);而6-MWD≥420m的慢性支气管炎患者与对照较差异无统计学意义(P>0.05).结论 6-MWT简便易行,可较好地反映患者的肺功能,可作为慢性支气管炎患者需做肺功能的筛选.

The value of six-minute walking test on chronic bronchitis needing lung function screening

Objective To study the relationship between the six-minute walking test (6-MWT) and pulmonary function in the diagnosis course of chronic bronchitis converting into chronic obstructive pulmonary disease (COPD). Methods Pulmonary function was detected in 360 patients with chronic bronchitis.Based on the results and diagnosis standard of COPD by Chinese Medical Association in 2002, the patients were divided into COPD group and pulmonary function normal group.Tbe walking distance in 6-MWT (6-MWD) was measured, and the mean value of twice tests was calculated to study the correlation between 6-MWT and pulmonary function, and 50 healthy volunteers were selected as control group. Results Most 6-MWD in COPD group were less than 420 meters(95.95%, 142/148 ), but those in pulmonary function normal group were more than or equalled to 420 meters mostly (97.17%, 206/212 ). However in patients with the 6-MWD more than or equalled to 420 meters , pulmonary function indexes such as the ratio of forced expiratory volume in one second and forced vital capacity( FVC ), FEV_1%, maximal ventilatory volume(MVV)were all significantly greater than those in patients with 6-MWD less than 420 meters, and there were significant differences (P<0.05). Compared with chronic bronchitis, the results of 6-MWD in control group was more than or equalled to 420 meters, but there was no significant difference (P>0.05 ). Conclusions 6-MWT is simple and feasible. However, it is a better indicator of the patients pulmonary function. The test would be an effective selecting examination for chronic bronchitis patients who are not willing to do puhnonary function test.