颈动脉粥样硬化斑块的声学密度定量分析

目的：探讨声学密度技术对颈动脉粥样硬化斑块组织定征诊断价值及其对斑块危险性的评估价值。方法：使用Hpsonos5500型彩色多普勒超声仪,采用AD技术分析50例患者76块斑块的背向散射积分（IBS值）及IBS标化值（IBS%值）,了解不同类型斑块的声学密度情况;对比有无脑梗死患者斑块的IBS值、IBS%值及不同类型斑块的发生率。结果：不同类型颈动脉粥样硬化斑块的发生率依次为扁平斑38.11%、软斑27.63%、硬斑22.37%、溃疡斑11.84%;不同类型斑块IBS值不同：硬斑34.32±1.10dB,扁平斑表面20.12±1.07dB,软斑与扁平斑内部相同15.93±0.71dB,溃疡斑8.41±1.03dB;IBS%亦不同,各组间比较有统计学差异（P〈0.05）;脑梗死组斑块IBS值及IBS%值均低于非脑梗死组（P〈0.05）;脑梗死组软斑和溃疡斑的比例高于非脑梗死组（P〈0.05）。结论：声学密度定量技术可反映粥样硬化斑块不同的组织成分;声学密度定量技术可评价颈动脉粥样硬化斑块的危险性。

Quantitative Study of Acoustic Densitometry on Carotid Artery Atherosclerosis Plaque

Objective:To assess the diagnose value of AD technique in carotid atherosclerosis plaque tissue characterization and the evaluate value of AD technique in the risk of carotid plaque.Methods:With color Doppler Ultrasonography,using AD technique,the AD values of 50 pationts with 76 carotid plaques,vessel wall and blood were measured.Compare the IBS and IBS% of plaque and the incidence of different type of plaques in patients with ischemic stroke and patiens without ischemic stroke.Results:The incidence of carotid artery atherosclerosis plaque:flat-plaque(38.11%);soft-plaque(27.63%);hard-plaque(22.37%);ulcer-plaque(11.84%);There are statistical intergroup differences in the AD values among the plaques:hard-plaque>flat-plaque>soft-plaque>ulcer-plaque;The IBS and IBS% of plaque in patiens with ischemic stroke is lower than patients without ischemic stroke.There are more soft-plaque and ulcer-plaque in patients with ischemic stoke.Conclutons:AD technique can evaluate the pathological components of carotid artery atherosclerosis plaque;AD technique can evaluate the risk of carotid artery atherosclerosis plaque;AD is a ultrasonic tissue characterization technique with high sensitivity,objectivity and accuracy.