辨证分型治疗腹泻型肠易激综合征随机平行对照研究

[目的]观察辨证分型治疗腹泻型肠易激综合征疗效。[方法]使用随机平行对照方法，将89例门诊及住院患者按随机数字表分为两组。对照组44例思密达，38／次，3次／d，口服。急性发作时，首次剂量加倍。治疗组45例辨证治疗。④肝郁脾虚，疏肝健脾。痛泻药方，白术30g，白芍、山药各20g，陈皮、柴胡各15g，防风、当归各10g，甘草5g；久泻加炒升麻6g，芡实10g；腹痛严重加木香6～9g，元胡6g。②脾胃湿热，清热化湿。黄芩、厚朴、薏苡仁、法半夏各12g，黄连4g，白扁豆15g，滑石20g。⑧脾胃虚寒，健脾暖胃。参苓白术散，白术、桔梗、白扁豆各15g，茯苓、党参、薏苡仁各20g，砂仁、炮姜、肉豆蔻各10g，大枣2片，炙甘草6g。④脾肾阳虚，温补脾肾。补骨脂30g，附子、炮姜、党参、苍术、白芍、陈皮、五味子各10g，防风12g，肉桂5g，甘草6g。1剂／d，水煎200mL，早晚口服。连续治疗28d为1疗程。观测临床症状、症状评分、不良反应。治疗1疗程，判定疗效。随访2个月，观察复发率。[结果]治疗组显效16例，有效25例，无效4例，总有效率91．1l％。对照组显效13例，有效19例，无效12例，总有效率72．73％。治疗组疗效优于对照组（P〈0．05）。症状评分两组均有改善，治疗组改善优于对照组（P〈O．01）。[结论]辨证分型治疗腹泻型肠易激综合征效果显著，值得推广。

Syndrome Randomized Parallel Controlled Study of TCM Syndrome Differentiation and Treatment of Diarrhea Predominant Irritable Bowel Syndrome

[ Objective ] To observe the TCM syndrome differentiation and treatment of diarrhea predominant irritable bowel syndrome. [ Methods ] Using randomized controlled Methods, 89 cases of outpatients and inpatients were randomly divided into two groups. A control group of 44 cases of smecta, 3g/, 3/d, oral. The acute attack, the first dose twice. The treatment group of 45 cases of TCM, ①The liver stagnation and spleen deficiency type ： expelling Shugan jianpi. Tongxieyaofang, Baishu 30g, Baoshao, Shanyao each 20g, Chenpi, Chaihu each 15g, Fangfeng, Danggui each 10g, Gancao 5g; Chronic diarrhea add Chaoshengma 6g, Qianshi 10g; Abdominal pain, severe add Muxiang 6 - 9g, Yuanhu 6g. ②The spleen and stomach damp heat type： treatment should be clearing heat, wet. Huangqin, Houpu, Yiyiren, Fabanxia each 12g, Huanglian 4g, Baibiandou 15g, Huashi 20g.③The spleen deficiency type： treatment should be Nuanwei spleen. Sherdingbaishu San, Baishu, Jiegeng, Baibiandou each 15g, Ftding, Dangshen, Yiyiren each 20g, Sharen, Paojiang, Roudonkou each 10g, Dazao 2pian, Zhigancao 6g.④The spleen kidney yang deficiency type ： appropriate treatment of Tonifying the spleen and kidney. Buguzhi 30g, Fuzi, Psaojiang, Dangshen, Cangshu, Baishao, Chenpi, Wuweizi each 10g, Fangfeng 12g, Rougui 5g, Gancao 6g. 1 doses of/d, water simmer in water to 200mL, sooner or later oral. Continuous treatment with 28d for 1 courses. Observation of clinical efficacy, symptom score, adverse reaction. 1 courses of treatment, the curative effect. Follow up of 2 months, to observe the relapse rate. 16 cases of group therapy [ Results ] 25 cases were effective, 4 cases ineffective, the total efficiency of 91.11%. The control group was 13 cases, effective 19 cases, invalid 12 cases, the total efficiency of 72.73%. The treatment group was better than control group （ P〈0.05 ） . The symptom score in treatment group than in control group （ P〈0.05 ） . The two groups were observed during the serious no adverse events. [ Conclusion ] TCM treatment of diarrhea type irritable bowel syndrome effect is siKnificant, worthy of promotion.