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Patterns of cerebral injury in a series of infants with congenital diaphragmatic hernia utilizing magnetic resonance imaging |
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| Authors: | Hunt Rod W Kean Michael J Stewart Michael J Inder Terrie E |
| Affiliation: | a Neonatal Neurology Department, Royal Children’s and Women’s Hospitals, Murdoch Childrens Rsearch Institute, Howard Florey Institute, University of Melbourne, Melbourne, Victoria, Australia b Department of Medical Imaging Royal Children’s Hospital, Melbourne, Victoria, Australia c Department of Neonatal Medicine, Royal Children’s Hospital, Melbourne, Victoria, Australia |
| Abstract: | BackgroundCongenital diaphragmatic hernia (CDH) is a condition with significant mortality and respiratory morbidity. Long-term neurodevelopmental outcome is not yet well documented.MethodsThe authors examined all cases of CDH at their institution over a 12-month period and performed magnetic resonance imaging (MRI) of the brain postoperatively.ResultsEight of 10 patients survived to have an MR brain scan. All 8 patients had cerebral injury detected on MRI, with a predominance of white matter and deep nuclear gray matter injury.ConclusionsCerebral injury detected with MRI is common in infants with congenital diaphragmatic hernia. The long-term significance of these MRI abnormalities is unknown, although the need for good long-term neurodevelopmental follow-up of infants with CDH is highlighted. |
| Keywords: | Congenital diaphragmatic hernia magnetic resonance imaging neurologic injury |
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