厄贝沙坦片和厄贝沙坦氢氯噻嗪片治疗轻中度高血压病疗效观察

目的比较厄贝沙坦片和厄贝沙坦氢氯噻嗪片对轻中度高血压患者的降压疗效。方法将80例轻中度高血压患者随机分为厄贝沙坦片治疗组（n=40）和厄贝沙坦氢氯噻嗪片治疗组（n=40）。结果治疗第8周时厄贝沙坦片治疗组和厄贝沙坦氢氯噻嗪片治疗组有效率分别为85%、90%（P〉0.05）。两组收缩压及舒张压均显著降低,两组间降压程度无显著性差异。结论两种药物均能有效降低血压。

A Comparison of Lrbesartan Tablets and Lrbesartan and HydrochloRothiazide Tablets for Treatment of Patients with Hypertension

Aim To compare the clinical effects of Irbesartan Tablets and Irbesartan and Hydrochlorothiazide Tablets in the treatment of hypertension.Methods Eighty patients with essential hypertension were randomly divided into two groups.The Irbesartan Tablet group(n=40) was treated with Irbesartan tablets 150mg per day while.Irbesartan and Hydrochlorothiazide Tablets group(n=40) was treated with Irbesartan and Hydrochlorothiazide tablets 150mg per day.The course of treatment was 8 weeks.Blood pressure and some biochemical parameters,such as liver and renal function,blood potassium,blood uric-acid and blood lipid,were evaluated before and after treatment.Result After 8 weeks of treatment,the effective rate of blood pressure control was 85% and 90% respectively without marked side-effects(P> 0.05).Conclusion Irbesartan Tablets and Irbesartan and Hydrochlorothiazide Tablets are effective and safe in the treatment of hypertension.