慢性腹泻与肠道需氧优势菌群的关系

探讨慢性腹泻与肠道需氧优势菌群的关系。方法取病人和健康人新鲜粪便分别接种于SS，MacConkey及血液琼脂平板上，35C24～48h后从均匀分布的单个菌落取l～3种优势生长的菌落数个进行鉴定，并进行统计分析。结果慢性腹泻患者以非大肠埃希氏菌为优势菌者占67．0％（73／109），分离出共22种76株细菌、3株真菌，其中G-杆菌17种55株，以奇异变形杆菌、弗劳地构林酸杆菌、液化沙雷氏菌、肺炎克雷伯氏菌为主，占58．0％（32／55）；G 球、杆菌5种21株，以屎链球菌、枯草芽胞杆菌为主，占71．4％（15／21）。30例健康人中未发现一例非大肠埃希氏菌优势生长者（P＜0．001）。结论慢性腹泻与肠道需氧优势菌群种类密切相关。

CHRONIC DIARRHEA AND INTESTINAL AEROBIC PREDOMINANT FLORA

Aim To determine the association of chronic diarrhea with intestinal aerobic predominantflora. Methods Fresh stools from patients and controls were inoculated on SS.,Mac Conkey and blood agar plates respectively and cultivated at 35 C for 24 ~ 48h, subsequent examinations of 1-3 species predominant colony from monocolony distributed over blood plates were made. Results Non-E. coli predominant flora were found in 73(67. 0% )patients with chronic diarrhea and none in controls (P<0. 001 ). The non--E. coli Predominant florain-cluded 22 species containing 76 strains bacteria and 3 strains fungii,of which G-bacilli were 17 species containing 55 strains, that mainly were Proteus mirabilis, Citrobacter freundii, Serratia liquetaciens, Klebsiella pneumoniae that possess 58. 0 % (32/55 ); G Cococci and Bacilli were 5 species containing 21 strains,mainly were Streptocococ-ci faecium and Baillus subtilis that possess 71. 4 % (15/21 ). Conclusion Chronic diarrhea correlates with the species of intestinal aerobic predominant flora. To our knowledge the correlation has not been reported.