肢端皮肤角化过度增生症的手术治疗

目的介绍肢端皮肤角化过度增生症１０例的治疗体会，其中掌跖角化病９例，疣状表皮结构不良１例。方法采用病变皮肤切除皮肤移植术治疗，其中两例有深部组织外露和放射性溃疡选用皮瓣修复，其余行皮片移植。结果１０例均获满意效果，追踪观察８年以上，无复发，能保持接近正常的功能活动。结论手部以皮片效果最佳，足底应用皮瓣修复，耐磨性较皮片为好，但因皮瓣缺乏纤维隔结构，走路时皮瓣与深部组织间产生相对滑动，也容易造成破溃，必须注意妥为保护

Surgical treatment of excessive hyperplasia symptom of skin keratosis at the limb ends\

Objective\ We introduce the experience of treating 10 cases with excessive hyperplasia of skin keratosis at the limb end.There were 9 cases of palmar and plantar keratosis and 1 case of epidermodysplasia verruciformis.Method\ All cases received the operation of lesion excision and skin grafting except 2 cases who received skin flap for defect covering after lesion excision because of deep tissue exposure and postradiation ulcer.Result\ The operative effects were satisfactory after 8 years of follow up.No recurrence was found in all cases and all patients resumed normal activity.Conclusion\ The effect of the skin flap is better than skin graft at the plantar area. Because of lack of fibrous septum in the subcutaneous tissue,the flap,often moving during walking,is liable to trauma and ulceration.The operation area must be well protected.