青木香(Aristolochia debillis Sieb.et Zucc.)的消炎和镇痛活性(英文)

目的:检测青木香(AristolochiadebillisSieb.etZucc.)的块根水提取液的消炎和镇痛效果及毒性。方法:用蛋清诱导法、热板法和扭体法。结果:青木香的块根水提取液无毒性,1000mg/kg,i.g.的青木香块根水提取液比生理盐水的消炎和镇痛效果明显,比200mg/kg,i.g.乙酰水杨酸的消炎效果好,2000mg/kg,i.g.的青木香块根水提取液比乙酰水杨酸的消炎效果更加显著。结论:青木香具有较好消炎和镇痛活性,无毒性。

Anti-inflammatory and Analgesic Activites of Aristolochia Debillis Sieb.et Zucc. Aqueous Extract

Objective:To determine anti-inflammatory, analgesic and acute toxicity effects of Aristolochia debillis Sieb.et Zucc. aqueous extract. Methods:Egg-albumin-induced edema in rats, hot-plate and acetic acid-induced abdominal constriction tests models respectively in mice were used. Results: The aqueous extract(1 000 mg/kg, i.g.)had significant analgesic and anti-inflammatory effects compared to physiological saline solution, and more significant anti-inflammatory effects compared to acetylsalicylic acid(200 mg/kg, i.g.). 2 000 mg/kg extract(i.g.)had a very significant anti-inflammatory effects compared to acetylsalicylic acid(200 mg/kg, i.g.). Conclusion: The aqueous extract had a significant analgesic and anti-inflammatory effects and had no acute toxicity.