| 西酞普兰治疗脑卒中后抑郁的对照研究 |
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| 引用本文： | 赵明,张永利,李梅香. 西酞普兰治疗脑卒中后抑郁的对照研究[J]. 中国健康心理学杂志, 2007, 15(8): 698-699 |
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| 作者姓名： | 赵明 张永利 李梅香 |
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| 作者单位： | 中国,河南新乡医学院第二附属医院神经内科,453002;中国,河南新乡医学院第二附属医院神经内科,453002;中国,河南新乡医学院第二附属医院神经内科,453002 |
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| 摘 要： | 目的 比较西酞普兰与丙米嗪治疗脑卒中后抑郁的疗效及安全性.方法 69例脑卒中后抑郁患者,随机分成两组.其中研究组35例,应用西酞普兰治疗;对照组34例,应用丙米嗪治疗;疗程均为6用.采用汉米尔顿抑郁量表、临床疗效总评定量表评定临床疗效,副反应量表评定药物的不良反应.结果 两组总体疗效相当(P＞0.05),但西酞普兰不良反应较丙米嗪组发生率低.结论 西酞普兰治疗脑卒中后抑郁疗效显著,不良反应少,安全性高.
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| 关 键 词： | 脑卒中后抑郁 西酞普兰 丙米嗪 副反应量表 |
| 收稿时间： | 2006-12-15 |
| 修稿时间： | 2006-12-15 |
A Comparative Study of Citalopram in the Treatment of Senile Depression |
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| Zhao Ming,Zhang Yongli,Li Meixiang. A Comparative Study of Citalopram in the Treatment of Senile Depression[J]. china journal of health psychology, 2007, 15(8): 698-699 |
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| Authors: | Zhao Ming Zhang Yongli Li Meixiang |
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| Affiliation: | The Second Affiliated Hospital of Xinxiang Medical College, Xinxiang 453002, P, R, China |
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| Abstract: | Objective To compare curative effects and safety of citalopram and imipramine in the treatment of post-stroke de- pression.Methods 69 patient with post-stroke depression were randomly divided into study(n=35,citalopram)and control group(n=34,imipramine)for 6 weeks.Clinical curative effects were assessed with the Hamilton Depression Scale(HAMD)and Clinical Global Impression(CGI)and side effects with the Treatment Emergent Symptom Scale(TESS).Results There was no significant difference in global curative effect between the two groups(P>0.05);citalopram took effect quicker,its side effects was milder.Conclusion Citalopram has significant curative efficacy,milder adverse reactions and higher safety in the treatment of post-strok depression. |
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| Keywords: | Post strok depression Citalopram Imipramine TESS |
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