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Experimental models of colorectal cancer |
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| Authors: | Anjan Banerjee M.Sc. M.S. D.M. Philip Quirke B.M. Ph.D. |
| Affiliation: | (1) From the Colorectal Unit, Department of Surgery, Royal Halifax Infirmary, University of Leeds Medical School, United Kingdom;(2) Leeds General Infirmary and University of Leeds Medical School, Leeds, United Kingdom;(3) Consultant Surgeon, Royal Halifax Infirmary, Free School Lane, HX1 2YP Halifax, United Kingdom |
| Abstract: | PURPOSE: A review ofin vivo andin vitro models of colorectal cancer is presented. METHODS: A retrospective literature review was performed with reference to CD-ROM Medline and Index Medicus. RESULTS: A comparison of the advantages and disadvantages of the models is presented in addition to a summary of individual model methodology and applications. CONCLUSIONS: Such models are a useful adjunct for surgical research in colorectal oncology.Mr. Banerjee is in receipt of support from the Yorkshire Cancer Research Organization. |
| Keywords: | Bile acid Carcinogen Cell lines Cancer Colorectal |
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