非酒精性脂肪肝患病率及其相关因素探讨

目的探讨某油田职工非酒精性脂肪肝（NAFL）患病率及其与肥胖、血脂异常、糖尿病的相关性。方法对743名某油田职工，测量身高、体重，行血脂、血糖、肝肾功能及腹部B超等检查，进行NAFL组和非NAFL组的对比分析。结果（1）743名职工中检出NAFL221名，检出率29．7％；其中BMI≥28者检出率为64．3％，BMI-Q24者检出率为13．4％，24≤BMI％28者检出率为48．6％；肥胖患者NAFL榆出率明显高于非肥胖者（P〈0．01）。（2）NAFL组的BMI、TG、HDL—C、FBG与非NAFL组比较，差异有统计学意义（P〈0．01）。（3）NAFL组中肥胖症、高脂血症、糖尿病的患病率显著高于非NAFL组（P〈0．01）。结论肥胖、血脂异常、糖尿病和高血压发生率NAFL组高于非NAFL组。

Prevalence of nonalcoholic fatty liver and its associated factors

Objective To investigate the prevalence of nonalcoholic fatty liver disease（NAFLD） in an oil field employees and its associated factors. Methods 743 emplyees received measurements of serum lipids, glucose,liver and renal function and ultrasonic examination of liver and kidney. Results （1）There were 221 NAFLD cases（30%） in all 743. The detection rate of NAFLD was 64% in subjects with BMI ≥28,and 13% with normal BMI.and 49% with 24≤〈BMI〈28. （2）The levels of TC,TG,LDL C,BMI and FIR3 were higher in NAFLD versus non-NAFLD group（P〈0.05）and HDL-C was lower in NAFLD. （3）NAFLD group showed the higher prevalences of obesity,hyperlipidemia and diasetes as compared with non-NAFLD（P〈0. 01） Conclusions The prevalence of NAFLD in employees of an oil field is higher than that of general population. Obesity, hyperlipidemia, and DM are closely related with NAFLD.