| 抗结核药物预防煤尘肺并发肺结核的效果观察 |
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| 引用本文： | 刘素芹,任建军,杨怀,曲峰,胡念岭,陈伟,王纪祥,陈广信.抗结核药物预防煤尘肺并发肺结核的效果观察[J].中国防痨通讯,2000,22(4):192-193. |
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| 作者姓名： | 刘素芹 任建军 杨怀 曲峰 胡念岭 陈伟 王纪祥 陈广信 |
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| 作者单位： | 1.安徽淮北矿务局卫生防疫站 235000； 2.淮北矿务局职业病防治院 235000； 3.安徽省结核病防治所 230022； |
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| 摘 要： | 目的 了解煤尘肺病人预防性服用异烟肼、利福平以减少煤尘肺病人并发肺结核的情况。方法 用双盲法将Ⅰ、Ⅱ期煤尘肺病人随机分为三组,分别服用异烟肼、利福平和安慰剂。结果 通过5年观察显示服异烟肼和利福平两组煤尘肺病人合并肺结核者明显低于服用安慰剂组(P<0.01)。结论 给予对煤尘肺患者实施预防性服用异烟肼、利福平可有效地减少肺结核的发生。
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| 关 键 词： | 结核 肺 煤尘肺 预防化疗 |
The effect of reducing incidence of TB by prophylactic chemotherapy in patients with coal-pneumoconiasis |
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| LIU Su-qin,REN Jian-jun,YANG Huai,et al..The effect of reducing incidence of TB by prophylactic chemotherapy in patients with coal-pneumoconiasis[J].The Journal of The Chinese Antituberculosis Association,2000,22(4):192-193. |
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| Authors: | LIU Su-qin REN Jian-jun YANG Huai |
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| Institution: | Sanitation and Anti-epidemic Station of Huaibei Mineral Office,Anhui 235000 |
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| Abstract: | Objective To observe the effect of reducing incidence of TB by prophylactic chemotherapy in cases with coal-pneumoconiasis.Methods 269 cases with stage Ⅰ,Ⅱ of coal-pneumoconiasis were devided to 3 groups and to take INH,RFP and placebo respectively for 3～6 months.Results Through after 5 years observation showed the incidence of TB was reduced signifficanly in the group A and group B (take INH or RFP) than The control group(P<0.01).Conclusion The prophylactic chemotherapy(INH,RFP) will reducing the incidence of TB in patients with coal-pneumoconiasis effectively. |
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| Keywords: | Tuberculosis pulmonary Coal-pneumoconiasis Prophylactic chemotherapy |
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