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An overview of high-dose melphalan and stem cell transplantation in the treatment of AL amyloidosis
Authors:Dr Vaishali Sanchorawala  David C. Seldin
Affiliation:1. Section of Hematology/Oncology in the Department of Medicine;2. Amyloid Treatment and Research Program, Boston University Medical Center, Boston, MA, USAVaishali.Sanchorawala@bmc.org;4. Amyloid Treatment and Research Program, Boston University Medical Center, Boston, MA, USA
Abstract:AL amyloidosis is the most common form of systemic amyloidosis and is associated with an underlying plasma cell dyscrasia. This review outlines an overview of high-dose intravenous melphalan and stem cell transplantation in the treatment of AL amyloidosis. An algorithm of our recommendations for the treatment of AL amyloidosis is also outlined.
Keywords:AL amyloidosis  treatment  stem cell transplantation  melphalan
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