Altered perception might be a symptom of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis |
| |
| Authors: | Michitaka Funayama Jin Mizushima Taketo Takata Akihiro Koreki Masaru Mimura |
| |
| Institution: | 1. Department of Neuropsychiatry, Ashikaga Red Cross Hospital, Ashikaga, Japanmctkfnym@gmail.com;3. Department of Neuropsychiatry, Ashikaga Red Cross Hospital, Ashikaga, Japan;4. Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan;5. Department of Neuropsychiatry, National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan;6. Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan |
| |
| Abstract: | ABSTRACTMost patients with N-methyl-D-aspartate receptor (NMDAR) encephalitis initially present with psychiatric symptoms. Although a delayed diagnosis may lead to a poor outcome, psychiatric symptoms that could differentiate anti-NMDAR encephalitis from other psychoses have not been fully investigated. We evaluated two patients with anti-NMDAR encephalitis who were observed by psychiatrists from onset throughout the course of disease. Both patients exhibited disorientation, memory deficits, perceptual disturbances, hallucinations, and mood liability. Among those, altered perceptions were most prominent - in particular, altered time perceptions without disorganization syndrome. The information obtained for these patients may help clinicians differentiate anti-NMDAR encephalitis from other psychoses, e.g., schizophrenia. |
| |
| Keywords: | Anti-NMDAR encephalitis altered time perceptions Alice in Wonderland syndrome schizophrenia |
|
|
