Early cognitive impairment in a subset of patients with presumed low-grade glioma |
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| Authors: | Lena Ek Ove Almkvist Maria Kristoffersen Wiberg Giuseppe Stragliotto Anja Smits |
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| Affiliation: | 1. Department of Psychology , Stockholm University , Stockholm, Sweden;2. Department of Geriatrics , University Hospital ?rebro , ?rebro, Sweden lena-birgitta.ek@telia.com;4. Department of Neurobiology, Care Sciences and Society (NVS) , Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden;5. Division of Radiology, Department of Clinical Science, Intervention and Technology (CLINTEC) , Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden;6. Department of Neurology , Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden;7. Department of Neuroscience , Neurology, Uppsala University, University Hospital , Uppsala, Sweden |
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| Abstract: | ![]()
We investigated the presence of cognitive impairment, in adults with presumed low-grade glioma at early stage of disease prior to major treatments, in relation to neurological symptoms and radiological characteristics of the tumour. Sixteen patients were evaluated. A subset of patients was identified with clearly impaired cognition. Patients with cognitive impairment often had large tumours in the left frontal lobe, were relatively young, and most of them were males. We conclude that cognitive dysfunction may be present already at early stage of disease, and that early identification of patients at risk is warranted. |
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| Keywords: | Low-grade glioma Brain tumour Cognition Depression MRI |
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