潘生丁负荷超声心动图对冠心病的早期诊断价值

目的探讨脉冲组织多普勒成像（PW-TDI）和潘生丁负荷试验对冠心病的早期诊断价值。方法选择冠心病患者73例（均为左前降支狭窄≥50%）,设正常对照组25例。所有病例均经冠状动脉造影证实。应用PW-TDI分别测量两组静息状态及潘生丁负荷状态下左室前壁、前间隔的室壁基底段和中段Vs、VE、VA值。结果静息状态下,冠心病组Vs、VE较对照组减低,且有显著性差异（P〈0.05）。单纯应用脉冲多普勒组织成像诊断冠心病敏感性80.3%、特异性72.1%。潘生丁负荷状态下,两组对应数据除VA外均差异明显增大,诊断冠心病敏感性93.6%、特异性86.1%。结论PW-DTI结合潘生丁负荷超声心动图对冠心病的早期诊断有肯定的应用价值。

Study on diagnosising coronary artery disease by pulse-wave Doppler tissue imaging and persantin stress test

Objective To assess the value of pulse-wave Tissue Doppler Imaging（PW-TDl） and persantin stress testin the diagnosis of coronary artery disease（CAD）. Methods Seventy-three patients with coronary artery disease underment coronary artery angiography were enrolled in the study.They were all with LAD stenosis ≥50%.Twenty-five patients with no coronary artery disease were as control group.Myocardial motion velocity in myocardial anterior wall and anterior-septal wall was measured with PW-TDI twice include before and during persantin stress test.TDI parameters included systolic peak velocity（Vs）,early and late diastolic peak velocity（VE and VA）. Results Vs and Ve of CAD group were decreased compared control group before persantin stress test（P〈0. 05 ）.These parameters became obvious at persantin stress.The sensitivity was 80.3% by PW-TDI to diagnosising coronary artery disease when the specificity was 72.1%. Compared persantin stress,the sensitivity was 93.6% and the specificity was 86.1%. Conclusions It is available for diagnosising coronary artery early disease by PW DTI and persantin stress test.