胫骨定量超声法检测骨质量的临床应用及评价

目的：通过马鞍山市区正常人群胫骨超声声速（SOS）的测定，达到对骨质疏松症作出早期诊断和预测骨折危险性，方法：用骨定量超声（QUS）仪检测1368例健康者右胫骨超声速度。各性能、年组之间进行比较，全部数据由计算机处理分析。结果：正常人SOS峰值（PV）炎性在40－49年龄组，女性在30－39年龄组。男性60岁以上各年龄组SOS下降，70岁以上明显下降（P＜0．01。女性40岁以上SOS即下降（P＜0．05）。50岁以上明显下降（P＜0．01）。40岁以前女性高于男性，50岁以后女性明显低于男性（P＜0．01）。结论：QUS对早期诊断骨质疏松和预测骨折危险性具有准确、快捷、无创伤等优点，从而为今后医疗保健提供依据。老年人胫骨SOS明显下降，老年女性下降更为明显，停经因素是导致骨质疏松的重要因素之一，与青年组比较，SOS减少2．0SD为骨质疏松症的诊断标准较适合本地区情况。

Clinical Application andEvaluation on Quantitative Ultrasound for Diagnosing Osteoporosis

Objective:The speed of ultrasound(SOS)which propagated through the right tibia of the healthy person was measured,so as to make early diagnosis of osteoporosis(OP)and predicting fracture risk.Methods:Using Sound Scan 2000,SOS of 1368 health volunteers in urban area of Ma an shan was investigated.All examinatorial data were processed by statistical method on the computer,including variance tests of significant differences.Results:All subjects were devided into groups according to sex and ten year age segments.The peak value of SOS was increased in age 30 39(female)and in age 40 49(male).The SOS was decreased rapidly above age 40 (female),but decreased slowly above age 40 (male).The mean value of SOS in menopause group is lower obviously than that of non menopause group.Conclusions:The method of quantitative ultrasound which can make early OP diagnosis and predicting fracture risk possesses rapid,non distructive and reliable advantages.The diagnostic standard of OP which below 2 0 SD of peak value group is comparative suitable for local conditions.