| 康泰仙对小鼠肝脑组织SOD、GSH—Px、CAT、MDA影响的实验研究 |
| |
| 引用本文： | 陈惠敏,程清洲,彭超华,徐静,王雪.康泰仙对小鼠肝脑组织SOD、GSH—Px、CAT、MDA影响的实验研究[J].医疗保健器具,2010,17(1):17-18. |
| |
| 作者姓名： | 陈惠敏 程清洲 彭超华 徐静 王雪 |
| |
| 作者单位： | 武汉工业学院,健康科学与护理系,湖北,武汉,430023 |
| |
| 基金项目： | 武汉工业学院科研资助课题 |
| |
| 摘 要： | 目的通过测定小鼠肝脑组织中超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH—Px）、过氧化氢酶（CAT）的活性和丙二醛（MDA）含量来研究康泰仙（KOTAIS）对小鼠抗衰老的作用。方法采用D-半乳糖制作的衰老模型，将小鼠随机分为正常组、模型组、药物低、中、高剂量组。连续给药灌胃60d后，检测肝脑组织中的SOD、GSH-Px、CAT、MDA指标。结果各剂量组能提高小鼠肝组织中SOD、GSH—Px、CAT的活性，并能降MDA的含量，以低、中剂量组尤其明显。结论康泰仙（KOTAIS）具有较好的消除自由基、抗衰老的作用。
|
| 关 键 词： | 康泰仙 超氧化物歧化酶 谷胱甘肽过氧化物酶 过氧化氢酶 丙二醛 肝脑组织 |
Experimental Study on SOD, GSH-Px, CAT, MDA Effects in Mice Liver and Brain Tissue of KOTAIS |
| |
| CHEN Huimin,CHENG Qingzhou,PENG Chaohua,XU Jing,WANG Xue.Experimental Study on SOD, GSH-Px, CAT, MDA Effects in Mice Liver and Brain Tissue of KOTAIS[J].Medicine Healthcare Apparatus,2010,17(1):17-18. |
| |
| Authors: | CHEN Huimin CHENG Qingzhou PENG Chaohua XU Jing WANG Xue |
| |
| Institution: | CHEN Huimin,CHENG Qingzhou,PENG Chaohua,XU Jing,WANG Xue (Health , Nursing Department of Wuhan Polytechnic University,Wuhan 430023,China) |
| |
| Abstract: | Objective To study the anti-aging effects of KOTAIS on model mice by measuring SOD, GSH-Px, CAT, MDA levels of liver and brain tissue. Methods Random groups were prepared by weight for 5 groups and were given normal, D-galactose, and the low, middle and high dose of KOTAIS. Interrelated senile indexes were measured after successively given medicine for 60 days. Results Every dose group is able to improve the activities of SOD and CAT and GSH-Px and decrease the level of MDA in the liver of all mice. The eff... |
| |
| Keywords: | KOTAIS SOD GSH-Px CAT MDA Liver and brain tissue |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
