800例肝炎肝硬化患者不同Child-Pugh分级的症状分布研究

目的:探索不同Child-Pugh分级肝炎肝硬化患者的症状分布特点,为肝炎肝硬化症状与Child-Pugh分级之间的关系进一步研究提供依据。方法:运用SPSS 20.0数据统计软件,根据通过《肝炎肝硬化临床信息采集表》收集到的800例肝炎肝硬化患者的的四诊信息资料,采用卡方分析法对97个症状进行检验,提取不同Child-Pugh分级之间具有统计学意义的症状,分析这些症状在不同Child-Pugh分级之间的分布特点,总结变化规律。结果:对800例肝炎肝硬化患者的97个症状进行卡方分析,发现从Child-Pugh A级到C级,腹水、黄疸、发热、浮肿等33个症状出现频率逐渐增加并且在各级之间均有统计学差异;急躁易怒、胁痛、薄苔等5个症状出现频率逐渐降低并且在各级之间均有统计学差异。结论:随着Child-Pugh分级由A级到C级的发展,肝炎肝硬化患者的病情逐渐加重,反映肝气郁结证的急躁易怒、胁痛等症状频率逐渐降低,而反映血瘀证、水湿停滞证、湿热证、气虚证、阴虚证、阳气虚证的肝掌、腹水、黄疸、乏力、裂纹舌、性欲减退等症状频率逐渐升高。

Research on Symptoms Distribution of Different Child-Pugh Grades in 800 Patients with Hepatitis Cirrhosis

Objective:To explore the distribution characteristics of symptoms of hepatocirrhosis patients in different Child-Pugh grades and provide the basis for the further study of the relationship between cirrhosis symptoms and Child-Pugh Grades.Methods:Using SPSS20.0 data statistics software,according to the collected data of 800 hepatocirrhosis patients from Clinical Information Collection form of hepatitis cirrhosis,to test 97 symptoms by chi-square analysis,extract the symptoms of statistical significance in different grades,analyze distribution characteristics of these symptoms and summarize the change rules.Results:By analyzing 97 symptoms of 800 patients by Chi-square analysis,it was founded that from Child-Pugh A to C level,the frequency of symptoms such as ascites,jaundice,fever and edema were gradually increased,which was statistically significant at all levels;The frequency of symptoms such as irritability,rib pain and thin moss were gradually decreased,which was statistically significant at all levels.Conclusion:As from Child-Pugh A to C level,patients with hepatitis cirrhosis are getting worse,the frequency of symptoms such as irritability and rib pain which reflect syndrome of liver-qi stagnation were gradually deduced,and the frequency of symptoms such as liver palm,ascites,jaundice,fatigue,crack tongue and sexual hypoactivity which reflect syndromes of blood stasis,water wet stagnation,damp-heat,Qi deficiency,Yin deficiency and Yang deficiency were gradually increased.