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Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis
Authors:Shigaku Ikeda  Hidetoshi Takahashi  Yasushi Suga  Hikaru Eto  Takafumi Etoh  Keiko Okuma  Kazuo Takahashi  Takeshi Kanbara  Mariko Seishima  Akimichi Morita  Yasutomo Imai  Takuro Kanekura
Affiliation:1. Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, Tokyo, Japan;2. Department of Dermatology, Asahikawa Medical University, Asahikawa, Japan;3. Department of Dermatology, Juntendo University Urayasu Hospital, Chiba, Japan;4. Department of Dermatology, St Luke''s International Hospital, Tokyo, Japan;5. Department of Dermatology, Tokyo Teishin Hospital, Tokyo, Japan;6. Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan;g Department of Dermatology, Yokohama City University Medical Center, Yokohama, Japan;h Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan;i Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan;j Department of Dermatology, Hyogo College of Medicine, Hyogo, Japan;k Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
Abstract:
Keywords:Dermatology Life Quality Index   edema   erythroderma   generalized pustular psoriasis   granulocytapheresis   granulocyte and monocyte adsorption apheresis   granulocytes and monocytes   neutrophilic pustules
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