Family history of affective illness in schizophrenia patients: Symptoms and cognition |
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Authors: | Deidre Anglin Arielle D. Stanford Jill M. Harkavy-Friedman Raymond Goetz Paul Rosenfield Dolores Malaspina |
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Affiliation: | aDepartment of Psychology, The City College and The Graduate Center, City University of New York, United States;bDepartment of Psychiatry, Columbia University, New York State Psychiatric Institute, United States;cDepartment of Psychiatry, New York University School of Medicine, United States |
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Abstract: | This study examined the relationship between having a family history of affective disorder and neuropsychological functioning and PANSS symptoms in schizophrenia patients falling into four exclusive family history groups (affective spectrum disorders, schizophrenia spectrum disorders, both, or neither). Schizophrenia patients with a family history of affective illness had the best performance on IQ tests and executive function measures. Symptoms showed fewer family history group differences. Schizophrenia patients with a family history of affective disorder may be a distinct subtype in the group of schizophrenias and may be biologically more similar to patients with serious affective disorder. |
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Keywords: | Affective Cognitive neuropsychology Family history Schizophrenia |
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