颈内动脉狭窄与脑梗死关系的研究(附76例报告)

目的探讨高血压病、2型糖尿病患者颅外段颈内动脉(ICA)狭窄与脑梗死的关系.方法选择年龄＞60岁的住院患者76例,分为三组:高血压病组26例,2型糖尿病组25例,高血压病合并2型糖尿病组25例;均进行颈部螺旋CT和头颅CT、MRI检查.结果高血压病合并糖尿病组患者的ICA重度狭窄(19例)较单纯高血压病组(10例)及单纯糖尿病组(10例)严重(P＜0.05);三组患者中ICA重度以上狭窄者,脑梗死的发生率明显高于轻-中度狭窄者(100.0%:24.3%)(P＜0.05).结论老年人高血压与糖尿病合并存在时,可加速动脉粥样硬化的发展;颅外段颈内动脉狭窄程度与脑梗死的发生有密切关系.

The relationship between cerebral infarction and stenosis of extracranial internal carotid artery in patients with hypertension and type 2 diabetes mellitus

Objective To study the relationship between cerebral infarction and stenosis of extracranial internal carotid artery in patients with hypertension(HT) complicated with type 2 diabetes mellitus(DM). Methods 76 patients(age>60 years old) were divided into 3 groups, 26 in hypertension group; 25 in DM group; 25 in hypertnsion complicated with DM. Carotid artery was detected by computed tomography angiography, and cranial CT?MRI were performed. Results The percentage of patients with severe stenosis of extracranial internal carotid artery in patients with hypertension complicated with type 2 diabetes mellitus were significantly higher than that in patients with hypertension or DM. The patients with severe stenosis of extracranial internal carotid artery were prone to develop cerebral infarction. Conclusions HT and DM can impact the development of atherosclerosis in senile patients. The stenosis of carotid artery is correlated with the incidence of cerebral infarction.