拉西地平与小剂量双氢克尿噻联用治疗老年单纯收缩期高血压疗效观察

目的 观察拉西地平与小剂量双氢克尿噻联用治疗老年单纯收缩期高血压疗效及不良反应.方法 入选126例年龄≥60岁单纯收缩期高血压病患者随机分为三组.A组拉西地平4mg/d,双氢克尿噻12.5mg/d联用;B组拉西地平4mg/d;C组双氢克尿噻25mg/d;各组疗程均为4周.结果 A组显效34例(81%),有效6例(14%),无效2例(5%),总有效率95%;B组显效21例(50%),有效10例(24%),无效11例(26%),总有效率74%;C组显效13例(31%),有效13例(31%),无效16例(38%),总有效率67%.结论 拉西地平与小剂量双氢克尿噻联用治疗老年单纯收缩期高血压疗效显著,不良反应少.

The curative and adverse effect o f Lacidipine united low dosage Aquarium in old ISH(isolated systolic hypertension)patients

Objective Aim To Study The curative and adverse effect o f Lacidipine united low dosage Aquarium in old ISH (isolated systolic hypertension) patients . Methods Three group were randomly divided in 126 cases whose ages were more than 60 years. Group A were used Lacidipine( 4 mg/d )united Aquarium (12.5mg/d) .Group B were used Lacidipine( 4 mg/d ). Group C were used Aquarium (25mg/d). Result 34 cases(81%)were excellent, 6 cases(14%)were utility, 2 cases (5%) were ineffective ,Total effective rate were 95% in group A . 21cases(50%)were excellent, 10 cases(24%) were utility, 11cases (26 %) were ineffective ,Total effective rate were 74% in group B.13 cases(31%)were excellent, 13 cases(31 %)were utility, 16cases (38%) were ineffective ,Total effective rate were 67% in group C. Conclusion The curative o f Lacidipine united low dosage Aquarium in old ISH(isolated systolic hypertension) patients were excellent and adverse effect were few .