Pyridones as Highly Selective,Noncovalent Inhibitors
of T790M Double Mutants of EGFR |
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| Authors: | Marian C. Bryan,Daniel J. Burdick,Bryan
K. Chan,Yuan Chen,Saundra Clausen,Jennafer Dotson,Charles Eigenbrot,Richard Elliott,Emily J. Hanan,Robert Heald,Philip Jackson,Hank La,Michael Lainchbury,Shiva Malek,Sam E. Mann,Hans E. Purkey,Gabriele Schaefer,Stephen Schmidt,Eileen Seward,Steve Sideris,Shumei Wang,Ivana Yen,Christine Yu,Timothy P. Heffron |
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| Affiliation: | †Genentech, South San Francisco, California 94080, United States;‡Argenta,Early Discovery Charles River, 7/9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR, United Kingdom |
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| Abstract: | | |
| Keywords: | Mutant EGFR noncovalent pyridone T790M |
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