Analysis of auditory brain stem response and otoacoustic emission in unilateral tinnitus patients with normal hearing |
| |
| Institution: | 1. Department of Otorhinolaryngology - Head and Neck Surgery, Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea;2. Republic of Korea Air Force, Gangneung, Republic of Korea;3. Department of Medical Informatics, Korea University College of Medicine, Seoul, Republic of Korea;1. Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaharacho, Shogoin, Sakyoku, Kyoto, Japan;2. Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan;3. Department of Radiation oncology and Image-applied therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan;1. Department of Otorhinolaryngology Head and Neck Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0375, Japan;2. School of Allied Health Science, Kitasato University, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa 252-0375, Japan;3. Department of Otolaryngology-Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan;4. Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa 252-0375, Japan;1. Indiana University, School of Medicine, Department of Medicine, United States;2. Department of Otorhinolaryngology, Jikei University, School of Medicine, Japan;3. Swallowing Center, The University of Tokyo Hospital, Japan;4. Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, the University of Tokyo, Japan;1. Department of Otolaryngology-Head and Neck surgery, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Republic of Korea;2. Department of Otolaryngology-Head and Neck surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Republic of Korea;3. Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea |
| |
| Abstract: | ObjectiveIn patients with unilateral tinnitus with normal hearing, several studies have compared the ipsilateral and contralateral ears; however, few studies have investigated its relationship with the duration of tinnitus. We compared the auditory brainstem response and otoacoustic emission parameters between ipsilateral and contralateral ears in adults with unilateral tinnitus and normal hearing.MethodsThis retrospective review included 84 patients with unilateral tinnitus and normal hearing who underwent auditory brainstem response and otoacoustic emission; they were categorized according to the duration of tinnitus. The latencies and amplitudes of waves I, III, and V, and V/I ratio of both ears in auditory brainstem response, and the results of distortion-product otoacoustic emission and transient evoked otoacoustic emission were examined. The auditory brainstem response parameters, distortion-product otoacoustic emission parameters, and transient evoked otoacoustic emission parameters between the ipsilateral and contralateral ears along the duration of tinnitus were analyzed. Moreover, the failure rates of both distortion-product otoacoustic emission and transient evoked otoacoustic emission between the ears along with the duration and the effects of the variables on the amplitude and latency of each wave were examined.ResultsIn this study, laterality seemed to have an effect on wave I latency in the multiple linear regression analysis. The distortion-product otoacoustic emission failure rate of the ipsilateral ear was higher than that of the contralateral ear in all patients. However, there was no remarkable difference between the ears in the distortion-product otoacoustic emission and transient evoked otoacoustic emission parameters throughout the duration.ConclusionWe found that outer hair cells and the distal portion of the cochlear nerve are possible pathologic lesions in tinnitus with normal hearing and cochlear synaptopathy could be suspected. Further studies, including those on inner hair cells and higher central cortex, are needed. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
