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French health insurance data for chronic rhinosinusitis with nasal polyps between 2011 and 2018: A STROBE-compliant analysis
Affiliation:1. Université de Lyon, université Lyon 1, hospices civils de Lyon, centre hospitalier Lyon Sud, service d’ORL, d’otoneurochirurgie et de chirurgie cervico-faciale, 69495 Pierre-Bénite cedex, France;2. Institut Mondor de recherche biomédicale Inserm-UPEC UMR 955, CNRS EMR 7000, 94010 Créteil, France;3. Inserm UMR 970, department of epidemiology, 75015 Paris, France;4. Service d’ORL et chirurgie cervico-faciale, Foch Hospital, 92150 Suresnes, France;5. École de Médecine, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), 92150 Suresnes, France;6. Université Paris-Saclay, AP–HP, hôpital Bicêtre, service d’ORL et de chirurgie cervico-faciale, DMU Neuroscience, Le Kremlin-Bicêtre, France;7. Institut Mondor de recherche biomédicale Inserm-UPEC UMR 955, CNRS ERL7000, 94275 Créteil, France;8. Service d’ORL, de chirurgie cervico faciale, hôpital Henri-Mondor, assistance Publique des hôpitaux de Paris, Créteil, France;9. Sanofi-Aventis France, 94250 Gentilly, France;10. Pierre Karam Conseil Santé, 69310 Ecully, France;1. Department of Otolaryngology, Head & Neck Surgery, Stanford University School of Medicine, 801 Welch Road, 94305-5739 Stanford, CA, USA;2. Department of Otolaryngology, Head & Neck Surgery, University Hospital of Toulouse Larrey, 24 Chemin de Pouvourville, 31059 Toulouse cedex 9, France;1. Département ORL, clinique Saint-Vincent, 8, rue de Paris, 97400 Saint-Denis, Île de la Réunion, France;2. Université Paris-Cité service d’oto-rhino-laryngologie et de chirurgie cervico-faciale, hôpital Européen Georges-Pompidou, AP–HP, 20–40, rue Leblanc, 75015 Paris cedex 15, France;1. Serviço de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350 - Santa Cecilia, 90035-007 Porto Alegre, Rio Grande do Sul, Brazil;2. Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Universidade Federal do Rio Grande do Sul (UFRGS), rua Ramiro Barcelos, 2400 sala 220, 90035-003 Porto Alegre, Rio Grande do Sul, Brazil;3. Unidade de Pneumologia Pediátrica, HCPA, Rua Ramiro Barcelos, 2350 - Santa Cecilia, 90035-007, Porto Alegre, Rio Grande do Sul, Brazil;1. Service d’ORL et chirurgie cervico-faciale, université Paris-Saclay, hôpital Bicêtre, AP–HP, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France;2. Département d’ORL et chirurgie cervico-faciale, CHU de Montpellier, hôpital Gui-de-Chauliac, 34295 Montpellier, France;3. Service d’ORL et de chirurgie cervico-faciale, centre hospitalier intercommunal de Créteil, 40, avenue de Verdun, 94000 Créteil, France;4. Service d’ORL et de chirurgie cervico-faciale, CHU d’Henri-Mondor, 8, rue Gustave-Eiffel, 94000 Créteil, France;5. Inserm, IMRB, université Paris Est Créteil, 94010 Créteil, France;6. CNRS ERL 7000, 94010 Créteil, France;7. Service d’ORL et chirurgie cervico-faciale, CHU de Poitiers, 86000 Poitiers, France;8. Service d’ORL, d’otoneurochirurgie et de chirurgie cervico-faciale, centre hospitalier Lyon Sud, hospices civils de Lyon, 69495 Pierre-Bénite cedex, France;9. Université de Lyon, université Lyon 1, 69003 Lyon, France;10. Service d’ORL et de chirurgie cervico-faciale, hôpital de Hautepierre, avenue Molière, 67098 Strasbourg, France;11. Unité Inserm 1121, biomatériaux et bioingénierie, 1, rue Eugène-Boeckel, 67000 Strasbourg, France;1. Service d’ORL et chirurgie cervico-faciale du CHU de Grenoble-Alpes (CHUGA), Grenoble, France;2. Faculté de médecine, universités des Alpes, Grenoble-Alpes (UGA), Grenoble, France;3. Laboratoire d’anatomopathologie, CHU de Grenoble-Alpes (CHUGA), Grenoble, France;4. Service de médecine nucléaire, CHU de Grenoble-Alpes (CHUGA), Grenoble, France
Abstract:AimsThe main aim of the present study was to report the annual volume of surgeries performed for chronic rhinosinusitis with nasal polyps (CRSwNP) in France, based on health insurance data. The secondary objectives were to describe the different characteristics of the surgeries and their complications, and to estimate the number of patients eligible for biotherapy.Material and methodsThis was a descriptive observational retrospective study using data from French national health insurance databases for the period 2011–2018. Inclusion criteria comprised all hospital stays with procedures related to CRSwNP according to the French Common Classification of Medical Acts and consistent with French practices.ResultsNinety-two thousand one hundred and fourty one patients (92,141) for 92,884 admissions for CRSwNP surgery were analyzed, providing an accurate representation of CRSwNP surgery in France between 2011 and 2018. The revision surgery rate for patients operated on in 2011 was 13.0% (1,457/11,212), corresponding to an average annual rate of 1.86% over 7 years. In the 11,750 sinus surgery admissions in 2018, the complications rate was only 0.65% (77/11,750).ConclusionSinus surgery is safe (0.65% complications) and reliable (estimated revision rate, 5.5%: 5,078/92,884). This study provides the first evaluation of the target population for biotherapy in France.
Keywords:Chronic rhinosinusitis with nasal polyps  Surgery  Complications  Epidemiology
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