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Treatment outcomes of sialendoscopy for submandibular gland sialolithiasis
Institution:1. Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Hokkaido, Japan;2. Department of Otolaryngology-Head and Neck Surgery, Hokuto Hospital, Obihiro, Hokkaido, Japan;1. Kyoto University Graduate School of Medicine, Department of Otolaryngology – Head & Neck Surgery, Kyoto, Japan;2. Japanese Red Cross Wakayama Medical Center, Department of Otolaryngology, Wakayama, Japan;1. Department of Otolaryngology-Head and Neck Surgery, Yokohama City University, Yokohama, Japan;2. Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University, Palo Alto, California, USA;3. Division of Head and Neck Surgery, University of California San Diego, La Jolla, California, USA;1. Department of Otorhinolaryngology Head and Neck Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0375, Japan;2. School of Allied Health Science, Kitasato University, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa 252-0375, Japan;3. Department of Otolaryngology-Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan;4. Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa 252-0375, Japan;1. Department of Otolaryngology-Head and Neck Surgery, Gifu University Graduate School of Medicine, Gifu City, Japan;2. Department of Plastic and Reconstructive surgery, Gifu University Hospital, Gifu City, Japan;3. Department of Gastroenterological Surgery and Pediatric Surgery, Gifu University Graduate School of Medicine, Gifu City, Japan;4. Department of Radiology, Gifu University Graduate School of Medicine, Gifu City, Japan;1. Division of Otolaryngology, Tohoku Medical and Pharmaceutical University Hospital, 1-12-1, Fukumuro, Miyaginoku, Sendai 983-8512, Japan;2. Department of Otolaryngology, Yamagata City Hospital Saiseikan, Yamagata, Japan;3. Division of Anatomy and Cell Biology, Tohoku Medical and Pharmaceutical University, 1-12-1, Fukumuro, Miyaginoku, Sendai 983-8512, Japan;4. Division of Pathology, Tohoku Medical and Pharmaceutical University, 1-12-1, Fukumuro, Miyaginoku, Sendai 983-8512, Japan
Abstract:ObjectiveSialendoscopy is a procedure used to remove salivary stones intraorally using a sialendoscope. In this study, we identified treatment outcomes of sialendoscopic surgery and identified predictive factors for successful stone removal by sialendoscopy alone.MethodsWe assembled the medical records of 144 patients who underwent sialendoscopic surgery for submandibular gland sialolithiasis at the Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, from October 2010 to November 2021, and collected patient backgrounds, medical condition, perioperative factors including operation method and complications, postoperative course, and stone constituents from a clinical laboratory testing company.ResultsSubmandibular gland stones were successfully removed using sialendoscopy in 58 patients (40%). In multivariate analysis, location, major axis, and mobility of the stones were independent factors for successful removal. In receiver operating characteristic analysis, <7.5 mm of a major axis may be used as a measuring standard for successful removal. Removal of parenchymal stones is prone to involve prolonged operation times, increased postoperative complications, and development of retained stones. The stones mainly consisted of calcium phosphate and protein, with content percentages ranging from 0 to 98% (median 37%) and from 0 to 100% (median 63%), respectively. The percentage of calcium phosphate was negatively correlated with the number of floating stones and successful stone removal.ConclusionSialendoscopy is an aesthetically attractive treatment for sialolithiasis that avoids cervical incisions. The present results showed not only known but also new predictive factors for the successful removal of stones (<7.5 mm) and percentage of calcium phosphate. Moreover, our results suggest that careful consideration is required regarding the indication of sialendoscopic surgery in patients with parenchymal stones.
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