Nasopharyngeal low-grade papillary schneiderian carcinoma with cervical metastasis |
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| Affiliation: | 1. Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan;2. Department of Diagnostic Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan;3. Department of Hematology, Oncology, Allergy and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan;1. Department of Head and Neck Surgery, Miyagi Cancer Center, 47-1 Nodayama, Medeshima-Shiode, Natori, Miyagi 981-1293, Japan;2. Department of Plastic and Reconstructive Surgery, Miyagi Cancer Center, 47-1 Nodayama, Medeshima-Shiode, Natori, Miyagi 981-1293, Japan;3. Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 2-1 Seriryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan;1. ENT institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China;2. NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai 20031, China;3. Shanghai clinical medical center of hearing medicine, Shanghai 200031, China;4. Otology and Neurotology of Miller School of Medicine, Miami University, 9375 SW 77th Avenue, #1019, 33156 Miami, USA;1. Department of Otolaryngology, The Second Hospital of Shandong University, Shandong University, No.274 Beiyuan Avenue, Jinan, Shandong Province, China;2. Department of Otolaryngology, Chengwu People''s Hospital (Chengwu Branch of the Second Hospital of Shandong University), No.66 Bole Avenue, Chengwu, Heze, Shandong Province, China |
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| Abstract: | Low-grade papillary Schneiderian carcinoma (LGPSC) is a rare and newly described type of cancer arising from the Schneiderian epithelium. Owing to cellular atypia, it is difficult to differentiate this type from other papillomas and malignancies. Although this condition remains unclear, it is associated with mortality and recurrence. Therefore, treating physicians should be aware of the possibility of LGPSC for prompt diagnosis and treatment. In this article, we present an additional case of nasopharyngeal LGPSC with cervical lymph node metastasis and reviewed the 14 cases reported thus far in the literature. A 76-year-old female was referred to our department for detailed examination of nasopharyngeal and cervical lymph node tumors detected by positron emission tomography-computed tomography. Based on the biopsy of the nasopharyngeal tumor, we suspected LGPSC. Considering the clinical course and pathological findings, the patient was diagnosed with cervical lymph node metastasis through neck dissection. We performed radiotherapy for the primary lesion of the nasopharynx, which led to the disappearance of the tumor. After 13 months following the radiotherapy, the patient died from a recurrence of retroperitoneal liposarcoma without the recurrence of LGPSC. |
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