靶控输注丙泊酚-氯胺酮静脉麻醉在剖宫产手术中的临床观察

目的：探讨靶控输注丙泊酚-氯胺酮静脉麻醉在剖宫产手术中的临床效果。方法172例择期剖宫产术的产妇，分为观察组86例和对照组86例。观察组采用静脉复合麻醉，麻醉药为丙泊酚、氯胺酮，进行靶控输注。对照组采用脊麻。对观察组和对照组胎儿娩出前和胎儿娩出后产妇的血氧饱和度（SpO2）、心率（HR）、收缩压（SBP）和舒张压（DBP）进行监测，新生儿1 min、5 min和10 min时的Apgar评分进行记录。结果观察组和对照组在胎儿娩出前、后SpO2、HR、SBP、DBP比较差异无统计学意义（P＞0.05），新生儿1 min、5 min和10 min时的Apgar评分比较差异无统计学意义（P＞0.05）。结论在剖宫产手术中应用靶控输注丙泊酚-氯胺酮静脉麻醉是可行的。

The application of intravenous anesthesia with the target controlled infusion of propofol-ketamine in cesarean section surgery

Objective To explore the application of intravenous anesthesia with the target controlled infusion of propofol-ketamine in cesarean section surgery. Methods 172 cases of parturient women undergoing elective cesarean section were selected. They were randomly divided into observation group and control group（n =86）. The compound intravenous anesthesia was used in observation group. And anesthetic was target control infusion of propofol and ketamine. The spinal anesthesia was adopted in control group. SpO2, HR, SBP and DBP of parturient women in observation group and control group were surveyed before fetal childbirth and after fetal childbirth. And Apgar scores of newborn in observation group and control group were recorded at 1 min, 5 min and 10 min. Results Comparison between groups：There was no statistically significant difference of SpO2, HR, SBP and DBP comparison in observation group and control group before fetal childbirth and after fetal childbirth（P〉0.05）. Comparison difference of Apgar scores for newborn in observation group and control group at 1 min, 5 min and 10 min had no statistical significance（P 〉 0.05）. Conclusion The application of intravenous anesthesia with target controlled infusion of propofol-ketamine in cesarean section surgery is feasible.