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| 翠云草中酚性成分的分离与鉴定 | |
| 引用本文： | 郑俊霞,王乃利,陈海峰,姚新生.翠云草中酚性成分的分离与鉴定[J].中国药物化学杂志,2007,17(5):302-305. |
| 作者姓名： | 郑俊霞 王乃利 陈海峰 姚新生 |
| 作者单位： | 1. 沈阳药科大学,中药学院,辽宁,沈阳,110016 2. 沈阳药科大学,中药学院,辽宁,沈阳,110016;深圳清华大学研究院,深圳市创新中药及天然药物研究,重点实验室,广东,深圳,518057 3. 深圳清华大学研究院,深圳市创新中药及天然药物研究,重点实验室,广东,深圳,518057;清华大学,医学院,北京,100084 |
| 基金项目： | 国家重点基础研究发展计划(973计划) |
| 摘 要： | 目的研究翠云草Selaginella uncinata(Desv.) Spring]的化学成分。方法利用硅胶、Sephadex LH-20、ODS柱色谱及反相制备型HPLC等方法进行分离纯化,根据化合物的理化性质及波谱数据鉴定它们的结构。结果与结论从体积分数为60%的乙醇提取液中分离得到7个酚性成分。结构分别鉴定为:阿魏酸棕榈酸-16-醇酯(1)、对羟基桂皮酸(2)、对羟基苯乙酮(3)、香草醛(4)、香草酸(5)、丁香酸(6)、对羟基苯甲酸(7)。化合物1~3为首次从该属植物中分离得到,化合物1~7为首次从该种植物中分离得到。 |
| 关 键 词： | 结构鉴定 柱色谱法 翠云草 酚性成分 |
| 文章编号： | 1005-0108（2007）05-0302-04 |
| 收稿时间： | 2007-01-23 |
| 修稿时间： | 2007年1月23日 |
Isolation and identification of phenolic constituents from Selaginella uncinata (Desv.) Spring |
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| ZHENG Jun-xia,WANG Nai-li,CHEN Hai-feng,YAO Xin-sheng.Isolation and identification of phenolic constituents from Selaginella uncinata (Desv.) Spring[J].Chinese Journal of Medicinal Chemistry,2007,17(5):302-305. | |
| Authors: | ZHENG Jun-xia WANG Nai-li CHEN Hai-feng YAO Xin-sheng |
| Institution: | 1. School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University, Shenyang 110016, China ; 2. Key Lab for New Drugs Research of TCM., Sheuzhen Research Institute of Tsinghua University, Shenzhen 518057, China ; 3. Medical School, Tsinghua University, Beijing 100084, China |
| Abstract: | Aim To study chemical constituents of Selaginella uncinata(Desv.)Spring.Methods The compounds were isolated by means of chromatography on silica gel,Sephadex LH-20 column,ODS column,and reversed-phase Pre-HPLC.Their structures were elucidated by spectroscopic analysis and chemical methods.Results and conclusion Seven phenolic compounds were obtained from the 60% ethanol extract of Selaginella uncinata(Desv.)Spring and their structures were identified as 16-feruloyloxypalmitic acid(1),p-hydroxycinnamic acid(2),1-(4-hydroxyphenyl)-ethanone(3),vanillin(4),vanillic acid(5),syringic acid(6),p-hydroxybenzoic acid(7).Compounds 1-3 were isolated from Selaginella genus for the first time,while compounds 1-7 were firstly obtained from Selaginella uncinata(Desv.)Spring. |
| Keywords: | structural identification column chromatography Selaginella uncinata(Desv )Spring phenolic constituents |
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