A comparative study on clinical characterizations between acute myelitis onset of neuromyelitis optica spectrum disease and idiopathic transverse myelitis |
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| Authors: | Zhuo Liu Meixin Xie Zhengjuan Lu Cunjin Zhang Huiping Chen Yun Xu |
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| Institution: | 1. Department of Neurology, Drum Tower Hospital, Medical School and the State Key Laboratory of Pharmaceutical Biotechnology, Institute of Brain Science, Nanjing University , Nanjing, China;2. Jiangsu Key Laboratory for Molecular Medicine, Medical School of Nanjing University , Nanjing, China;3. Jiangsu Province Stroke Center for Diagnosis and Therapy , Nanjing, China;4. Department of Neurology, The People’s Hospital of Luhe, 9 Jiankang Lane , Nanjing, Jiangsu Province, PR China;5. Jiangsu Province Stroke Center for Diagnosis and Therapy , Nanjing, China;6. Nanjing Neuropsychiatry Clinic Medical Center , Nanjing, China |
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| Abstract: | ABSTRACT Background/Aims Both of neuromyelitis optica spectrum disease (NMOSDs) and idiopathic transverse myelitis (ITM) could present as acute transverse myelitis. However, long-term immunological treatment and prognosis are different for high recurrence of NMOSDs. In this study, we summarized clinical differences between acute attack myelitis of NMOSDs and ITM, we further screened serum auto-antibodies to help understand the two distinct clinical entities. |
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| Keywords: | NMOSD idiopathic transverse myelitis auto-antibodies clinical parameters |
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