Biomarkers of liver fibrosis: prospective comparison of multimodal magnetic resonance,serum algorithms and transient elastography |
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| Authors: | Mikael F. Forsgren Patrik Nasr Markus Karlsson Nils Dahlström Bengt Norén Simone Ignatova |
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| Affiliation: | 1. Department of Radiation Physics, Department of and Health, Medicine and Caring Sciences, Link?ping University, Link?ping, Sweden;2. Center for Medical Image Science and Visualization (CMIV), Link?ping University, Link?ping, Sweden!["ORCID]("//:0" "\"ORCID") https://orcid.org/0000-0003-4630-6550;3. Department of Gastroenterology and Hepatology, Department of Health, Medicine and Caring Sciences, Link?ping University, Link?ping, Swedenhttps://orcid.org/0000-0002-2928-4188;4. Center for Medical Image Science and Visualization (CMIV), Link?ping University, Link?ping, Swedenhttps://orcid.org/0000-0002-9876-8274;5. Center for Medical Image Science and Visualization (CMIV), Link?ping University, Link?ping, Sweden;6. Department of Radiology, Department of and Health, Medicine and Caring Sciences, Link?ping University, Link?ping, Swedenhttps://orcid.org/0000-0002-4111-1693;7. Department of Radiology, Department of and Health, Medicine and Caring Sciences, Link?ping University, Link?ping, Swedenhttps://orcid.org/0000-0002-6422-9520;8. Department of Clinical Pathology and Clinical Genetics, Department of Biomedical and Clinical Sciences, Link?ping University, Link?ping, Swedenhttps://orcid.org/0000-0001-5734-8276 |
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| Abstract: | AbstractBackground and aimsAccurate biomarkers for quantifying liver fibrosis are important for clinical practice and trial end-points. We compared the diagnostic performance of magnetic resonance imaging (MRI), including gadoxetate-enhanced MRI and 31P-MR spectroscopy, with fibrosis stage and serum fibrosis algorithms in a clinical setting. Also, in a subset of patients, MR- and transient elastography (MRE and TE) was evaluated when available. |
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| Keywords: | Elastography MRE Gadoxetate-enhanced MRI 31P-MR spectroscopy serum fibrosis algorithms liver fibrosis |
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!["ORCID]({"type":"image","src":"/templates/jsp/images/orcid.png"} "\"ORCID")
https://orcid.org/0000-0003-4630-6550;3. Department of Gastroenterology and Hepatology, Department of Health, Medicine and Caring Sciences, Link?ping University, Link?ping, Sweden