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8种预防胆囊炎、胆石症手术感染用药方案的成本-效果分析
引用本文:林朝仙,蔡小燕,佘白蓉,蔡木禹.8种预防胆囊炎、胆石症手术感染用药方案的成本-效果分析[J].中国药房,2005,16(12):913-914.
作者姓名:林朝仙  蔡小燕  佘白蓉  蔡木禹
作者单位:广东汕头大学医学院附属第一医院,汕头市,515041
摘    要:目的:评价8种用药方案预防胆囊炎、胆石症手术感染的经济效果。方法:运用药物经济学原理对氨苄西林+阿米卡星+甲硝唑(A)、氨氯西林+甲硝唑(B)、左氧氟沙星+甲硝唑(C)、头孢哌酮/舒巴坦+甲硝唑(D)、头孢他啶+甲硝唑(E)、哌拉西林/他唑巴坦+甲硝唑(F)、头孢曲松+甲硝唑(G)、头孢噻肟/舒巴坦+甲硝唑(H)8种用药方案的成本-效果进行分析。结果:A、B、C、D、E、F、G、H8组成本分别为72.75、497.75、339.75、392.75、1213.95、931.75、315.75、1409.75元,A组成本最低;效果各组间无显著性差异。结论:A方案为较佳选择。

关 键 词:胆囊炎  胆石症  手术感染  用药方案  成本-效果分析
文章编号:1001-0408(2005)12-0913-02
修稿时间:2005年5月10日

Cost- effectiveness Analysis of 8 Medication Schemes for Preventing Postoperative Infection of Cholecystitis and Cholelithiasis
LIN Chaoxian,CAI Xiaoyan,SHE Bairong,CAI Muyu.Cost- effectiveness Analysis of 8 Medication Schemes for Preventing Postoperative Infection of Cholecystitis and Cholelithiasis[J].China Pharmacy,2005,16(12):913-914.
Authors:LIN Chaoxian  CAI Xiaoyan  SHE Bairong  CAI Muyu
Abstract:OBJECTIVE:TO evaluate the economic effectiveness of the8medication schemes for preventing postoperation infections of cholecystitis and cholelithiasis.METHODS:The principle of pharmacoeconomics was adopted in the cost-effec-tiveness analysis of8medication schemes,ampicillin amikacin metroidazole(A),ampicloxacillin metroidazole(B),lev-ofloxacin metroidazole(C),cefoperazone/sulbactam metroidazole(D),ceftazidime metroidazole(E),piperacillin/tazobac-tam metroidazole(F),ceftriaxone metroidazole(G),cefotaxim/sulbactam metroidazole(H).RESULTS:The costs for A,B,C,D,E,F,G and H schemes were72.75,497.75,339.75,392.75,1213.95,931.75,315.75and1409.75yuan respec-tively,with scheme A the lowest in cost;No significant differences were found in effectiveness among the8schemes.CON-CLUSION:Scheme A is superior to the others.
Keywords:Cholecystitis  Cholelithiasis  Postoperative infection  Medication scheme  Cost-effectiveness analysis
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